In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Xiaobo WuTranslational Biology, Medicine, and Health Graduate Program, Virginia Polytechnic Institute and State University, Roanoke, Virginia.ORCID 0000-0002-3136-5059 Sharon A SwangerCenter for Neurobiology Research, Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, Virginia, USA.ORCID 0000-0003-0615-6244 Gregory S HoekerCenter for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, Virginia, USA.ORCID 0000-0002-3917-4791 Rowan MaisonneuveTranslational Biology, Medicine, and Health Graduate Program, Virginia Polytechnic Institute and State University, Roanoke, Virginia.
Peter CarmelietLaboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, 3000, Belgium.ORCID 0000-0001-7961-1821 Robert G GourdieCenter for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, Virginia, USA.ORCID 0000-0001-6021-0796 Seth H WeinbergDepartment of Biomedical Engineering, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0003-1170-0419 Steven PoelzingCenter for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, Virginia, USA.ORCID 0000-0002-6979-1264 Funding
PATTERNING OF GAP JUNCTION COUPLING IN DEVELOPING HEARTR01HL056728 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GOURDIE, ROBERT G · 1997 to 2021
$5.6MConnexin-based Signaling in the Heart: Cellular and ExosomalR35HL161237 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ROBERT G GOURDIE · 2022 to 2026
$4.4MRole of the Extracellular Space as a Modulator of the Cardiac Gap Junction - Conduction Velocity RelationshipR01HL102298 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI POELZING, STEVEN · 2011 to 2020
$3.9MSignaling in Inherited and Acquired Sodium Channel Gain of FunctionR01HL138003 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI POELZING, STEVEN, WEINBERG, SETH HOWARD · 2018 to 2021
$2.6MTherapeutic Targeting of Voltage Gated Sodium Channel AutoregulationR01HL169610 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Steven Poelzing, Seth Howard Weinberg · 2024 to 2026
$2.1MThe Role of the Sodium Channel Beta Subunit in Cardiac ConductionR01HL141855 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GOURDIE, ROBERT G, POELZING, STEVEN · 2018 to 2021
$1.8MNHLBI NIH HHS R01 HL056728NHLBI NIH HHS R01 HL102298NHLBI NIH HHS R01 HL138003NHLBI NIH HHS R01 HL141855NHLBI NIH HHS R01 HL169610NHLBI NIH HHS R35 HL161237
6 · The paper itselfAbstract
Cardiac voltage-gated sodium channel gain-of-function (Na Objective: Determine whether hypernatremia and perinexal expansion synergistically prolong APD in an animal model functionally expressing I Methods: Whole-cell I Results: In isolated myocytes, hypernatremia (160mM sodium) increased I Conclusions: Hypernatremia during Na
Indexed as
Basic Science ResearchCongenital Heart DiseaseElectrophysiologyTranslational Studies
Identifiers
PMID41427381
PMCPMC12713656
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