Evidence map›Paper›PMID 41427378›Full record

ArticlebioRxiv : the preprint server for biology2025

A microgel bone marrow model of mesenchymal stem cell paracrine signaling supporting hematopoietic stem cell retention.

Gunnar B Thompson, Kaila M Kuo, Andrés J García, Brendan A C Harley

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gunnar B ThompsonDept. Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0003-2139-8700
Kaila M KuoDept. Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Andrés J GarcíaParker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, GA 30332.ORCID 0000-0001-6602-2518
Brendan A C HarleyDept. Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-5458-154X

Funding

Gradient Biomaterials to Investigate Niche Regulation of HematopoiesisR01DK099528 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Brendan A. Harley · 2014 to 2026
$4.0M
NIDDK NIH HHS R01 DK099528
6 · The paper itself

Abstract

Hematopoietic stem cells (HSCs) housed within the bone marrow give rise to the full complement of blood and immune cells. Methods to expand HSCs

Indexed as

bone marrowgelatinhematopoietic stem cellmesenchymal stromal cellmicrogel

Identifiers

PMID41427378
PMCPMC12712932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.