Evidence map›Paper›PMID 41427314›Full record

ArticlebioRxiv : the preprint server for biology2026

Process for Standardizing and Assessing the Parameters Governing MS2 Virus-Like Particle Reassembly around Nucleic Acid Cargo.

Daniel de Castro Assumpcao, Emma S Vinokour, Madeline M Mills, Shiqi Liang, Carolyn E Mills, Aline Carvalho da Costa, Nolan W Kennedy, Danielle Tullman-Ercek

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Daniel de Castro AssumpcaoDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0002-9973-3241
Emma S VinokourWeinberg College of Arts and Sciences, Northwestern University, Evanston, Illinois, USA.ORCID 0009-0009-9826-2319
Madeline M MillsDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0002-3868-3199
Shiqi LiangInterdisciplinary Biological Sciences Program, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0002-1933-6941
Carolyn E MillsDepartment of Bioengineering, University of California, Santa Barbara, California, USA.ORCID 0000-0001-6058-0762
Aline Carvalho da CostaSchool of Chemical Engineering, University of Campinas, Campinas, Sao Paulo, Brazil.
Nolan W KennedyDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0002-2944-5439
Danielle Tullman-ErcekDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0001-6734-480X

Funding

Molecular Biophysics Training Program at Northwestern UniversityT32GM140995 · NIGMS · NORTHWESTERN UNIVERSITY · PI Heather Wendy Pinkett, Reza Vafabakhsh · 2021 to 2026
$2.5M
Chemistry of Life Processes Predoctoral Training ProgramT32GM149439 · NIGMS · NORTHWESTERN UNIVERSITY · PI NEIL L KELLEHER · 2023 to 2026
$1.6M
NIGMS NIH HHS T32 GM140995NIGMS NIH HHS T32 GM149439
6 · The paper itself

Abstract

MS2 virus-like particles (VLPs) are widely used as protein nanocages for cargo encapsulation, yet

Indexed as

Capsid assemblydesign of experimentsself-assembly

Identifiers

PMID41427314
PMCPMC12714026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.