Evidence map›Paper›PMID 41427307›Full record

ArticlebioRxiv : the preprint server for biology2025

Mechanism of NanR transcriptional activation of sialic acid metabolism in

David M Wood, Ashleigh S Johns, Zachary D Tillett, Heather L Shearer, Santosh Panjikar, Yee-Foong Mok, Michael D W Griffin, Timothy M Allison, Rachel A North, Paul E Pace and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David M WoodBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, PO Box 4800, Christchurch 8140, New Zealand.ORCID 0000-0002-8275-3510
Ashleigh S JohnsBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, PO Box 4800, Christchurch 8140, New Zealand.ORCID 0000-0002-0630-4270
Zachary D TillettBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, PO Box 4800, Christchurch 8140, New Zealand.ORCID 0009-0001-3522-195X
Heather L ShearerMātai Hāora - Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8041, New Zealand.ORCID 0000-0001-8191-7723
Santosh PanjikarAustralian Synchrotron, ANSTO, Clayton, 800 Blackburn Road, Victoria 3168, Australia.ORCID 0000-0001-7429-3879
Yee-Foong MokDepartment of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0002-4252-9426
Michael D W GriffinDepartment of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0001-9845-7735
Timothy M AllisonBiomolecular Interaction Centre, School of Physical and Chemical Sciences, University, of Canterbury, Christchurch, New Zealand.ORCID 0000-0003-4100-6700
Rachel A NorthSchool of Medical Sciences, Faculty of Medicine and Health, University of Sydney, New South Wales 2006, Australia.ORCID 0000-0001-5011-1567
Paul E PaceMātai Hāora - Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8041, New Zealand.ORCID 0000-0003-0195-3949
Borries DemelerDepartment of Chemistry and Biochemistry, University of Lethbridge, 4401 University Drive, Lethbridge, AB T1K 3M4, Canada.ORCID 0000-0002-2414-9518
Mark B HamptonMātai Hāora - Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8041, New Zealand.ORCID 0000-0002-7349-3729
Renwick C J DobsonBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, PO Box 4800, Christchurch 8140, New Zealand.ORCID 0000-0002-5506-4939
Christopher R HorneBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, PO Box 4800, Christchurch 8140, New Zealand.ORCID 0000-0003-1318-514X

Funding

Development of an UltraScan Meta-Scheduler for HPC Job SubmissionR01GM120600 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Emre H. Brookes, BORRIES DEMELER · 2016 to 2026
$3.6M
NIGMS NIH HHS R01 GM120600
6 · The paper itself

Abstract

In

Indexed as

cooperativitycryo-electron microscopyNanRNeu5AcRpiR superfamilysialic acidStreptococcus pneumoniaetranscriptional regulatorX-ray crystallography

Identifiers

PMID41427307
PMCPMC12713135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.