Evidence map›Paper›PMID 41427293›Full record

ArticlebioRxiv : the preprint server for biology2025

Non-apoptotic death of the

Olya Yarychkivska, Simin Liu, Lauren Bayer Horowitz, Shiloh Newland, Peipei Wu, Saiya Mittal, Shogo Tamura, Tetiana Novosolova, David Faulkner Ritter, Yun Lu and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Olya YarychkivskaLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.ORCID 0000-0002-0048-1006
Simin LiuLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.
Lauren Bayer HorowitzLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.ORCID 0000-0003-0385-7555
Shiloh NewlandLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.
Peipei WuCSHL; Cold Spring Harbor, USA.
Saiya MittalLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.
Shogo TamuraLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.
Tetiana NovosolovaLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.
David Faulkner RitterDepartment of Biology and the Center for Genomics and Systems Biology, New York University, New York, 10003.ORCID 0009-0004-5449-0698
Yun LuLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.
Sevinç ErcanDepartment of Biology and the Center for Genomics and Systems Biology, New York University, New York, 10003.ORCID 0000-0001-7297-1648
Christopher HammellCSHL; Cold Spring Harbor, USA.ORCID 0000-0002-5961-0976
Shai ShahamLaboratory of Developmental Genetics, The Rockefeller University; New York, 10065, USA.ORCID 0000-0002-3751-975X

Funding

Glial Control of Neuron Development and Function - Administrative SupplementR35NS105094 · NINDS · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2018 to 2025
$8.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
OSCILLATORY GENE EXPRESSION AND THE MAINTENANCE OF TEMPORAL PATTERNINGR01GM117406 · NIGMS · COLD SPRING HARBOR LABORATORY · PI HAMMELL, CHRISTOPHER MARTIN · 2016 to 2025
$4.0M
Mechanisms of condensin-mediated gene regulation in C. elegansR35GM130311 · NIGMS · NEW YORK UNIVERSITY · PI Sevinc Ercan · 2019 to 2026
$3.3M
Linker cell death regulation in C. elegansR01HD103610 · NICHD · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2021 to 2025
$1.8M
Nuclear and chromatin aberrations during non-apoptotic cell death in C. elegans and mammalsK99GM151467 · NIGMS · ROCKEFELLER UNIVERSITY · PI YARYCHKIVSKA, OLGA · 2023 to 2024
$250k
NICHD NIH HHS R01 HD103610NIGMS NIH HHS K99 GM151467NIGMS NIH HHS R01 GM117406NIGMS NIH HHS R35 GM130311NIH HHS P40 OD010440NINDS NIH HHS R35 NS105094
6 · The paper itself

Abstract

Linker cell-type death (LCD) is a morphologically conserved non-apoptotic cell-death process with features resembling polyglutamine-dependent neurodegeneration. In

Identifiers

PMID41427293
PMCPMC12712910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.