Evidence map›Paper›PMID 41427169›Full record

ArticleACS omega2025

Frutalin as an Affinity Tool for sIgA1: Biophysical and Structural Characterization of the Lectin-Antibody Complex.

Roberta C C Costa, Talita A Leite, José G S Gomes, Francisco P F Silva, Marcus R L Bezerra, Wallady S Barroso, Gilvan P Furtado, André L C Silva, Bruno A M Rocha

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In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roberta C C CostaDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.ORCID https://orcid.org/0000-0001-5857-1576
Talita A LeiteDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.
José G S GomesDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.
Francisco P F SilvaDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.
Marcus R L BezerraOswaldo Cruz Foundation, R. São José, S/N - Precabura, Eusébio 61760-000, Brazil.
Wallady S BarrosoTaqMol Diagnostics, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.ORCID https://orcid.org/0000-0001-8026-5778
Gilvan P FurtadoOswaldo Cruz Foundation, R. São José, S/N - Precabura, Eusébio 61760-000, Brazil.
André L C SilvaDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.
Bruno A M RochaDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Av Humberto Monte s/n, Fortaleza 60440-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secretory immunoglobulin A1 (sIgA1) is the predominant antibody in mucosal secretions and human colostrum, where it plays critical roles in immune exclusion and microbiota regulation. Due to its high degree of glycosylation, oligomeric variability, and structural flexibility, selective purification of sIgA1 remains a technical challengeyet essential for biomedical, immunological, and biotechnological applications, including diagnostic platforms and passive immunotherapy. In this study, frutalin (FTL), a galactose-specific lectin from

Identifiers

PMID41427169
PMCPMC12713436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.