ReviewMaterials today. Bio2025
Harnessing biomaterials for tuning inflammation: A neutrophil-centric perspective.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation is crucial in combating infection, tissue repair, and immune regulation. However, dysregulated inflammatory responses induce and exacerbate numerous systemic diseases, even posing life-threatening risks. Neutrophils, the most abundant white blood cells in the bloodstream, are vital to the innate immune system. In recent years, neutrophils have been discovered to exhibit phenotypic heterogeneity and functional plasticity, capable of regulating various biological processes and impacting human diseases. Furthermore, neutrophils and their derivatives can serve as natural sources for biomaterials to control inflammatory responses. In this timely review, we begin by outlining the complex functions of neutrophils in inflammatory responses. Subsequently, we summarize the design strategies for neutrophil-based biomaterials. Afterward, we list and analyze the advancements in neutrophil-based anti-inflammatory biomaterials. Finally, we explore the challenges and prospects in this area. This review aims to provide a comprehensive understanding of harnessing neutrophils as a therapeutic target.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.