ArticleFrontiers in neurology2025
Factors associated with progression and sex-specific patterns in chronic subdural hematoma: a single-centre retrospective study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to identify determinants of chronic subdural hematoma (CSDH) progression and to evaluate potential sex-related differences. Methods: Patients with unilateral CSDH were retrospectively enrolled between January 2018 and December 2024. Data on demographics, clinical characteristics, hematoma density, hematological parameters and coagulation function were collected. Multivariable logistic regression was used to identify independent predictors. Patients were randomly divided into training and validation cohorts in a 7:3 ratio to identify factors associated with hematoma progression. Subsequently, logistic regression models were applied to both cohorts to confirm the factors influencing progression. Results: This retrospective study enrolled 1,142 patients, who were categorized into progression ( Conclusion: Elevated INR, hypertension, diabetes, NLR, WBC, and MaHD were independently associated with CSDH progression. Female sex conferred a protective effect. These findings require prospective validation.
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