Evidence map›Paper›PMID 41426984›Full record

ArticleFrontiers in neurology2025

Predicting efficacy of combined functional electrical stimulation combined with mirror therapy in post-stroke lower limb dysfunction: development and validation of a nomogram model.

Wei Wang, Guobin Zhao, Genchun Guo

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei WangSport and Health College of Shinhan University, Uijeongbu-si, Gyeonggi-do, Republic of Korea.
Guobin ZhaoSport and Health College of Shinhan University, Uijeongbu-si, Gyeonggi-do, Republic of Korea.
Genchun GuoDepartment of Rehabilitation Medicine, Affiliated Hospital 6 of Nantong University (Yancheng Third People's Hospital), Yancheng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the predictive factors of the efficacy of conventional therapy combined with functional electrical stimulation combined with mirror therapy (FES-MT) in the treatment of lower limb dysfunction after cerebral infarction, and to construct and validate a nomogram prediction model to assist in clinical precision treatment. Methods: A total of 212 patients with lower limb dysfunction after cerebral infarction, who received the aforementioned treatment, were enrolled retrospectively. Based on therapeutic efficacy, they were divided into an effective group and an ineffective group. Relevant clinical indicators were collected. Patients were randomly assigned in a 7:3 ratio to a training set ( Results: Among the 212 patients, 142 were classified as effective and 70 as ineffective. Multivariate logistic regression analysis showed that longer time from onset to treatment, higher fasting plasma glucose, higher homocysteine, larger infarct volume, higher National Institutes of Health Stroke Scale score, and lower pre-treatment Fugl-Meyer score (lower limb) were independent risk factors for ineffective treatment. The constructed nomogram model exhibited C-index values of 0.890 and 0.872 in the training and validation sets, respectively, with mean absolute errors of 0.124 and 0.114. In the Hosmer-Lemeshow test, the χ Conclusion: The nomogram prediction model, based on the identified influencing factors, demonstrates excellent predictive performance for the clinical efficacy of conventional therapy combined with FES-MT in patients with lower limb dysfunction after cerebral infarction. This model facilitates clinical outcome prediction and aids in formulating individualized treatment strategies.

Indexed as

cerebral infarctionfunctional electrical stimulation mirror therapylogistic analysislower limb motor dysfunctionnomogram prediction model

Identifiers

PMID41426984
PMCPMC12715374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.