Evidence map›Paper›PMID 41426956›Full record

ArticlemicroPublication biology2025

Mitochondrial polarization and redox homeostasis couple glycolysis-to-OXPHOS metabolic rewiring to lifespan extension in

Anwaar Ali, Shanmuganathan Balakrishnan, Jiayu Xiang, Haesoo Bae, Minou Tsujishita, Amina Abulimiti, Bence Nemeth, Michalis Barkoulas, Kambiz N Alavian

Abstract read
In one paragraph

Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anwaar AliDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Shanmuganathan BalakrishnanDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Jiayu XiangDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Haesoo BaeDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Minou TsujishitaDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Amina AbulimitiDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Bence NemethDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.
Michalis BarkoulasDepartment of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, England, United Kingdom.
Kambiz N AlavianDepartment of Brain Sciences, Faculty of Medicine, Imperial College London, London, England, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are essential for maintaining cellular homeostasis throughout life. Here, we investigated the differential effects of glucose and galactose, as well as glycolytic inhibition, on

Identifiers

PMID41426956
PMCPMC12714341

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.