Evidence map›Paper›PMID 41426947›Full record

ArticleInfant and child development

Brain morphometry of toddlers with language delay: An exploratory study.

Courtney A Filippi, Elizabeth Smith, Elizabeth Redcay, Heather Hazlett, Lauren Thompson, Stacy S Manwaring, Precilla D'Souza, Audrey Thurm

Abstract read
In one paragraph

Article in Infant and child development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Deep learning in fetal, infant, and toddler neuroimaging research.Developmental cognitive neuroscience · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Courtney A FilippiEmotion and Development Branch, National Institute of Mental Health, Bethesda, Maryland, 20892.
Elizabeth SmithDivision of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
Elizabeth RedcayDepartment of Psychology, University of Maryland, College Park, Maryland, 20742.
Heather HazlettCarolina Institute for Developmental Disabilities and Department of Psychiatry, University of North Carolina at Chapel Hill, NC 27599.
Lauren ThompsonDepartment of Speech and Hearing Sciences, Elson S. Floyd College of Medicine, Washington State University.
Stacy S ManwaringDepartment of Communication Sciences and Disorders, University of Utah.
Precilla D'SouzaNeurodevelopmental and Behavioral Phenotyping Service, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland 20892.
Audrey ThurmNeurodevelopmental and Behavioral Phenotyping Service, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland 20892.

Funding

Neurodevelopmental and Behavioral Phenotyping ZICMH002961 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI THURM, AUDREY · 2017 to 2025
$12.6M
Identifying neural markers of risk for anxiety in infancyR00MH125878 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FILIPPI, COURTNEY · 2023 to 2025
$733k
Intramural NIH HHS ZIC MH002961NIMH NIH HHS R00 MH125878
6 · The paper itself

Abstract

While studies have documented neural correlates of language delay in toddlers with developmental conditions, those at genetic risk for language delay, and those born premature, no studies have examined neural correlates in toddlers exhibiting early language delay without known etiology. This study examines brain morphometry in toddlers with and without early language delay. To do so, we collected magnetic resonance imaging on toddlers with language delay (LD; n=7, M

Indexed as

middle temporal gyrusneurodevelopmental disorderssurface area

Identifiers

PMID41426947
PMCPMC12714334

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.