ArticleCureus2025
Assessment of Retinal Function Using Full-Field Electroretinography in Patients Undergoing Vitrectomy for a Macular Hole.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Applications of Photopic Negative Response: A Narrative Review.Journal of clinical medicine · 2026Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose The aim of this study was to evaluate retinal function before and after vitrectomy in patients with a full-thickness macular hole (FTMH). Methods A total of 48 patients with FTMHs confirmed by spectral-domain optical coherence tomography (OCT) were enrolled. All underwent 23-gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and gas tamponade. Retinal function was assessed using the RETeval™ (LKC Technologies, Inc., Germantown, MD) device before surgery and at one, three, six, and 12 months postoperatively. Electroretinography (ERG) recordings included standard photopic responses, photopic negative response (PhNR), and ON-OFF responses. Anatomical outcomes were evaluated using OCT. Results Statistical analysis was completed for 48 patients. Postoperative anatomical closure of the macular hole was achieved in all cases. A significant improvement was observed in both distance best corrected visual acuity (DBCVA) and near best corrected visual acuity (NBCVA) of the affected eye after surgery compared to preoperative values (p < 0.001). No significant differences were found between the ERG parameters of the affected eye and the healthy eye examined before surgery. Postoperatively, several photopic ERG implicit times (ITs) were prolonged in the operated eyes compared with the fellow eyes. Conclusions The RETeval™ system provides a non-invasive, standardized means of monitoring retinal function in patients with FTMHs undergoing vitrectomy. An FTMH appears to be a localized phenomenon, not associated with significant functional impairment of the entire retina, as evidenced by the lack of statistically significant differences in preoperative ERG parameters between the affected and fellow healthy eyes.
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