Evidence map›Paper›PMID 41426856›Full record

ArticleCureus2025

"Look What the Cat Dragged In": Delayed-Onset Hypersensitivity Pneumonitis Due to Pregnancy.

Robin Roberts, Angharad Rowles, Hana Alachkar, Claire Kilduff

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robin RobertsMedicine, Ysbyty Gwynedd Hospital, Bangor, GBR.
Angharad RowlesMedicine, Ysbyty Gwynedd Hospital, Bangor, GBR.
Hana AlachkarImmunology, Royal Liverpool University Hospital, Liverpool, GBR.
Claire KilduffRespiratory Medicine, Ysbyty Gwynedd Hospital, Bangor, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypersensitivity pneumonitis (HP) is an immune-mediated inflammatory lung disease triggered by the inhalation of environmental antigens. Bird fancier's lung is a common subtype, whereby the hypersensitivity reaction is triggered by exposure to avian proteins from bird feathers and droppings. This case describes a woman in her 20s, presenting at 16 weeks postpartum, with progressive dyspnoea, dry cough, and hypoxia. A thorough social history revealed significant exposure to a pigeon after the woman had rescued a pigeon from her cat and nursed it back to health during her third trimester. Computed tomography (CT) imaging revealed diffuse pulmonary nodules and air trapping, and subsequent serology confirmed elevated IgG to avian proteins. The patient was diagnosed with bird fancier's lung and managed with corticosteroids. The pigeon was relocated to avoid further exposure. It is proposed that the Th2-dominant immune profile during pregnancy leads to an anti-inflammatory state, suppressing Th1-driven conditions such as HP and delaying symptom onset until the postpartum immune rebound. Recognition of this immunological shift is critical in postpartum patients with atypical respiratory symptoms. Timely history-taking, specialist input, and consideration of environmental triggers were key to swift diagnosis and management in this case.

Indexed as

avian proteinbird fancier's lungenvironmental allergenhypersensitivity pneumonitismultiple lung nodulesperipartum physiological changespulmonary immunology

Identifiers

PMID41426856
PMCPMC12712409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.