ReviewCureus2025
Diagnostic Performance of Vessel Wall Magnetic Resonance Imaging (VW-MRI) for Intracranial Vasculopathies: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Contrast-enhanced ultrasound detection of a longitudinal fissure-like intraplaque channel associated with plaque-fragment embolization during carotid artery stenting: a case report.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vessel wall magnetic resonance imaging (VW-MRI) provides superior capabilities, compared to traditional angiography, in evaluating intracranial vessel walls. This study aimed to assess the diagnostic performance of VW-MRI in intracranial vasculopathies. This systematic review and meta-analysis followed PRISMA guidelines. PubMed, Scopus, Web of Science, Cochrane Library, and ScienceDirect were searched to identify studies investigating the diagnostic performance of VW-MRI in intracranial vasculopathies. Eligible studies should report sufficient data to construct 2 × 2 contingency tables. Disease categories were included only if at least two studies were available. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), and area under the curve (AUC) were estimated using a bivariate model. Study quality was assessed using the QUADAS (Quality Assessment of Diagnostic Accuracy Studies) tool. Ten studies on intracranial atherosclerotic disease (ICAD) demonstrated high diagnostic accuracy (sensitivity 0.877; specificity 0.808; DOR 34.2; AUC 0.907). Subgroup analyses confirmed reliability in detecting stenosis, distinguishing culprit from non-culprit lesions, and identifying eccentric wall thickening as a biomarker. Six studies on intracranial vasculitis showed strong diagnostic performance of concentric wall enhancement (sensitivity 0.817; specificity 0.864; DOR 44.9; AUC 0.909). Two studies on intracranial dissection reported high accuracy (sensitivity 0.901; specificity 0.829; DOR 58.1; AUC 0.930). VW-MRI demonstrates excellent diagnostic performance for ICAD, intracranial vasculitis, and dissection. It provides added value beyond conventional imaging by enabling evaluation of vessel wall features and lesion characterization. Further high-quality studies, with larger sample sizes, are needed to validate its clinical utility.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.