ReviewCureus2025
Quality of Life of Patients Undergoing Heart Valve Interventions: An Integrative Review of Studies Using the 36-Item Short Form Health Survey (SF-36) Questionnaire.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Valvular heart disease represents a significant burden on global health, and its impact on health-related quality of life (HRQOL) is increasingly recognized in clinical decision-making. This integrative review synthesized outcomes measured with the 36-Item Short Form Health Survey (SF-36). A structured PubMed search was conducted in November-December 2024 and updated in September 2025; studies published from 2014 onward that reported SF-36 after heart valve interventions were included. Twelve studies met the criteria, spanning surgical and transcatheter approaches and both mechanical and biological prostheses. Across studies, early (≤1 month) improvements were evident, with the largest gains typically in physical domains. Mid-term (six to 12 months) improvements were generally sustained, and differences between transcatheter and surgical approaches tended to attenuate, with no consistent between-group differences by six to 12 months in studies reporting adjusted comparisons. Age-related patterns were observed: older patients started lower and showed smaller absolute gains in physical domains, while mental health changes were more modest and often comparable across ages. Findings comparing mechanical versus biological valves were heterogeneous and likely influenced by confounding (age, comorbidity, anticoagulation). Longer-term (>12 months) trajectories remain uncertain due to limited longitudinal data. Limitations include the single-database search restricted to English-language and free full-text articles, variability in follow-up windows and reporting, and the absence of a formal meta-analysis or risk-of-bias grading. Despite these constraints, current evidence indicates that heart valve interventions improve HRQOL, supporting shared decision-making and the need for standardized time points, adjusted analyses, and longer follow-up to refine comparative inferences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.