Evidence map›Paper›PMID 41426794›Full record

ArticleCureus2025

Cardiac Complications in Women With Hypertensive Disorders of Pregnancy Undergoing a Cesarean Section: Role of Intraoperative Hemodynamic Monitoring.

Wajeeha Fatima, Azfar Rahim, Zainab Nisar, Izza Mahoor, Ghulam Sughra, Warda Raja, Jawad Hameed, Muhammad Ammar Hasan, Muhammad Anas Ahmed, Jassim Zaheen Shah

Abstract read
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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Wajeeha FatimaObstetrics and Gynaecology, Mid City Hospital, Lahore, PAK.
Azfar RahimObstetrics and Gynaecology, Sindh Institute of Child Health and Neonatology, Karachi, PAK.
Zainab NisarObstetrics and Gynaecology, Sindh Institute of Child Health and Neonatology, Karachi, PAK.
Izza MahoorAnaesthesia, Avicenna Medical College, Lahore, PAK.
Ghulam SughraObstetrics and Gynaecology, Asian Institute of Medical Sciences, Hyderabad, PAK.
Warda RajaDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, PAK.
Jawad HameedAnesthesia and Critical Care, Lady Reading Hospital, Peshawar, PAK.
Muhammad Ammar HasanObstetrics and Gynaecology, Letterkenny University Hospital, Letterkenny, IRL.
Muhammad Anas AhmedMedicine, Shaikh Zayed Hospital, Lahore, PAK.
Jassim Zaheen ShahCardiology, Heart Hospital, Doha, QAT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Hypertensive disorders of pregnancy (HDP) are major contributors to maternal morbidity and mortality, predisposing to significant cardiac complications during cesarean section. Hemodynamic fluctuations under anesthesia further increase the risk of myocardial ischemia, arrhythmia, and pulmonary edema. Continuous intraoperative monitoring may help identify early hemodynamic instability and improve maternal outcomes. Objective This study aimed to evaluate the frequency, pattern, and predictors of maternal cardiac complications in women with HDP undergoing cesarean section and to determine the protective role of intraoperative hemodynamic monitoring. Methods This retrospective study was conducted at Lady Reading Hospital MTI, Peshawar, Pakistan, over 24 months (January 2023-December 2024). Medical records of 250 women aged 18-45 years with HDP undergoing cesarean section were reviewed. Data included demographic features, disease subtype, anesthesia type, intraoperative hemodynamic parameters, monitoring modality, and postoperative outcomes. Maternal cardiac complications were defined as arrhythmia, pulmonary edema, myocardial ischemia, heart failure, or hemodynamic instability occurring intraoperatively or within 48 hours postoperatively. Data were analyzed using IBM SPSS Statistics for Windows, version 26.0. Independent t-tests and Chi-square tests were applied, and logistic regression identified independent predictors (p < 0.05 considered significant). Results Among 250 women, preeclampsia was the most common subtype (162; 64.8%), followed by eclampsia (48; 19.2%) and gestational hypertension (11.2%). Overall, 54 (21.6%) developed maternal cardiac complications. Advanced maternal age (≥35 years), elevated body mass index (BMI) (≥28 kg/m²), and general anesthesia were independently associated with increased cardiac risk (p < 0.05). Invasive intraoperative hemodynamic monitoring significantly reduced the likelihood of undetected hemodynamic deterioration (adjusted odds ratio (OR) 0.48; 95% confidence interval (CI) 0.25-0.94; p = 0.031). Patients with complications had longer hospital stays and higher ICU admission rates. Conclusion Maternal cardiac complications are common in women with HDP undergoing a cesarean section, especially among older and obese patients and those receiving general anesthesia. Invasive hemodynamic monitoring provides a protective benefit and should be considered in high-risk patients to enhance perioperative safety and improve outcomes.

Indexed as

cardiac complicationscesarean sectionhemodynamic monitoringhypertensive disorders of pregnancymaternal outcomes

Identifiers

PMID41426794
PMCPMC12712732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.