ArticleCureus2025
The Enigma of Large-Sized, Multiple Tuberous Xanthomas: A Report of a Rare Case.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
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Abstract
This case report presents a rare case of multiple xanthomas in a 20-year-old man, highlighting the clinical implications and underlying health concerns associated with such lesions. The patient exhibited multiple large tuberous xanthomas that developed over several years and were associated with familial hypercholesterolemia and valvular heart disease. A comprehensive diagnostic workup revealed significantly elevated cholesterol levels, echocardiographic findings consistent with valvular dysfunction, and characteristic xanthomatous lesions on imaging and histopathological examination. The patient underwent a multifaceted treatment approach, including dietary modifications, pharmacotherapy, and surgical excision of the lesions, to alleviate discomfort and improve quality of life. The findings underscore the necessity of heightened awareness among healthcare providers regarding the potential systemic implications of xanthomas, advocating for early diagnosis and intervention to mitigate associated cardiovascular risks. The limitations of this study include a lack of genetic testing, which could further elucidate the pathophysiology of the condition. This report emphasizes the importance of a holistic treatment strategy that combines surgical and medical management to address both the physical and psychological burdens of this condition while preventing recurrence.
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