ArticleCureus2025
Acral Melanosis with Macromelanosomes (AMM): The First AI-Defined Pathological Entity and Proposal of Provisional Diagnostic Criteria.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Artificial intelligence (AI) has started to transform diagnostic workflows in pathology, yet no formal pathological entity has been named, defined, and documented in the medical literature by an AI system. We report a benign acral pigmentary process characterized by conspicuous keratinocyte macromelanosomes with otherwise normal melanocyte density and architecture. We propose the term "acral melanosis with macromelanosomes (AMM)," a name and construct first generated with the assistance of a large language model (ChatGPT), and we present clinical, histologic, and special‑stain findings along with provisional diagnostic criteria.
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