ArticleFrontiers in public health2025
Comparative analysis of trends in the burden of pancreatitis in China and worldwide, 1990-2021.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy and safety of Xuesaitong injection as adjuvant therapy for acute pancreatitis: a systematic review and meta-analysis.Frontiers in pharmacology · 2026Pooled it
- The Joint Global Epidemiology of Pancreatic Cancer and Pancreatitis: Co-Occurrence Patterns, Shared Risk Factors, and Projections to 2040.United European gastroenterology journal · 2026Article
- Metagenomic landscape of peripancreatic necrotic pus in acute pancreatitis: pathogen ecology, resistance gene profiles, and disease-associated microbial patterns.Frontiers in microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Amidst global demographic aging patterns, understanding divergent trajectories of pancreatitis burden is crucial for health equity. This study compares China's pancreatitis burden (1990-2021) against global aggregates, focusing on age-sex stratification within aging populations. Methods: Leveraging Global Burden of Disease 2021 datasets, we analyzed age-standardized rates (ASR) for incidence (ASIR), prevalence (ASPR), mortality (ASMR), and disability-adjusted life years (DALYs/ASDR). Joinpoint regression quantified temporal trends via average annual percentage changes (AAPC). Statistical significance was determined through 95% confidence intervals (CIs). GBD standardization protocols ensured comparability of sex-age stratified analyses. Results: From 1990 to 2021, China witnessed significant declines in pancreatitis burden. The age-standardized rates per 100,000 population fell as follows: incidence (ASIR) from 35.35 to 23.95; prevalence (ASPR) from 35.33 to 24.15; mortality (ASMR) from 0.98 to 0.64; and DALYs (ASDR) from 29.77 to 18.27. The corresponding average annual percentage changes (AAPCs: ASIR -1.34%; ASPR -1.25%; ASMR -1.40%; ASDR -1.57%) were substantially greater than the global averages (ASIR -0.44%; ASPR -0.99%; ASMR -0.47%; ASDR -0.53%). Age and sex disparities were clear, with males having higher rates below age 65, and females bearing a greater burden thereafter. Conclusion: This study highlights a marked decline in China's pancreatitis burden, linked to healthcare advances, despite persistent disparities in older populations. Moving beyond isolated descriptions of trends, our study introduces a direct comparative analysis that quantifies China's steeper decline in pancreatitis burden relative to the global average. This provides a nuanced, quantitative benchmark for evaluating the effectiveness of national health policies. These findings call for equitable policies and future work on region-specific risks and scalable interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.