Evidence map›Paper›PMID 41426593›Full record

ArticleFrontiers in medicine2025

Successful ventilator weaning after aerosolized liposomal amphotericin B in persistent

Massimo Caracciolo, Simona Pellicano, Sarah Antonella Caracciolo, Maria Francesca Stagno, Antonino Ripepi, Selma Valerie Mammone, Nadia Pellicano, Stefano La Scala, Giuseppe Mazza, Giuseppe Neri

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Massimo CaraccioloUOSD Post-Operative Intensive Care Unit, Great Metropolitan Hospital Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Simona PellicanoUOSD Post-Operative Intensive Care Unit, Great Metropolitan Hospital Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Sarah Antonella CaraccioloUOC Perioperative and General Anesthesia and Intensive Care, Senese University Hospital, Siena, Italy.
Maria Francesca StagnoUOSD Post-Operative Intensive Care Unit, Great Metropolitan Hospital Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Antonino RipepiUOSD Post-Operative Intensive Care Unit, Great Metropolitan Hospital Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Selma Valerie MammoneUOC Anesthesia and Intensive Care, San Pio X Hospital Humanitas, Milan, Italy.
Nadia PellicanoUOSD Post-Operative Intensive Care Unit, Great Metropolitan Hospital Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Stefano La ScalaUOSD Post-Operative Intensive Care Unit, Great Metropolitan Hospital Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Giuseppe MazzaAnesthesia and Intensive Care, Department of Medical and Surgical Sciences, Magna Grecia University, Catanzaro, Italy.
Giuseppe NeriAnesthesia and Intensive Care, Department of Medical and Surgical Sciences, Magna Grecia University, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive candidiasis and persistent fungal colonization of the airways are increasingly recognized as potential barriers to successful weaning from mechanical ventilation in critically ill patients. Among Case presentation: We present the case of a 68-year-old man who required prolonged mechanical ventilation following an ischemic stroke and subsequently developed persistent bronchial colonization by Conclusion: This case highlights the potential role of aerosolized liposomal amphotericin B as an effective and well-tolerated treatment for persistent fungal airway colonization by

Indexed as

Aerogen vibrating mesh deviceaerosolized amphotericin BCandida glabrata Nakaseomyces glabratafungal colonizationICUimmune evasionliposomal formulationventilator weaning

Identifiers

PMID41426593
PMCPMC12711831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.