SynthesisFrontiers in medicine2025
Effects of the computer-assisted rehabilitation environment on patient rehabilitation: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Computer-assisted rehabilitation environment (CAREN) integrates virtual reality, motion capture systems, and real-time feedback mechanisms to enhance patient rehabilitation results. This study aimed to determine the potential benefit of CAREN in increasing balance, cognition, and mental health in patients with neurological and musculoskeletal disorders. Methods: Systematic searches were carried out across PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), and Web of Science databases for relevant studies published up to November 2025. The review comprised randomized, non-randomized controlled trials and single-arm studies evaluating the rehabilitative outcomes of CAREN treatment compared with standard therapy or no intervention in patients. The primary outcomes comprised balance function, cognitive functions, and mental health status; the secondary outcome was the incidence of adverse events. The quality of studies included in the review was evaluated using the Newcastle-Ottawa Scale, and the pooled effect size was computed using standardized mean differences (SMDs) or mean differences (MDs) for continuous outcomes. Statistical analysis was performed using Stata 18.0. Results: The database search yielded 3,553 records, of which 15 studies were included, and 9 had sufficient data for meta-analysis. CAREN training significantly improved balance, as indicated by higher Berg Balance Scale scores (SMD = 1.12; 95% CI = 0.08 to 2.16; Conclusion: CAREN training appears to improve balance and cognitive function, while its effects on mental health are relatively limited. However, these findings should be interpreted with caution. Systematic review registration: PROSPERO, identifier (CRD420251172390).
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