Evidence map›Paper›PMID 41426523›Full record

ArticleSurgical case reports2025

Pancreatic-Type Acinar Cell Carcinoma of the Duodenum: A Case Report and Literature Review.

Daisuke Shirai, Seiko Hirono, Masaharu Tada, Kenjiro Iida, Hideaki Sueoka, Ami Kurimoto, Mizuki Yoshida, Kazu Harada, Chisato Ohe, Hiroshi Kono and 1 more

Abstract readCase Reports
In one paragraph

Article in Surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daisuke ShiraiDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Seiko HironoDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Masaharu TadaDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Kenjiro IidaDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Hideaki SueokaDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Ami KurimotoDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Mizuki YoshidaDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Kazu HaradaDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Chisato OheDepartment of Diagnostic Pathology, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Hiroshi KonoDepartment of Diagnostic Pathology, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Ikuo NakamuraDivision of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcinar cell carcinoma (ACC) is a rare malignant tumor arising from pancreatic exocrine cells. While it typically originates in the pancreas, ectopic occurrences, especially in the duodenum, are extremely uncommon. Few reports exist of duodenal ACC, particularly those presenting as large tumors. CASE PRESENTATION: An 83-year-old man presented with melena. Endoscopy and imaging revealed a large mass, approximately 7 cm in size, extending from the duodenal bulb to the descending portion of the duodenum. Contrast-enhanced CT showed no evidence of extramural invasion or distant metastasis. Although biopsy confirmed malignancy, a definitive diagnosis could not be established preoperatively. The patient underwent pancreaticoduodenectomy. Postoperative histopathological examination, including immunohistochemical staining positive for trypsin, confirmed the diagnosis of pancreatic-type ACC, likely arising from ectopic pancreatic tissue in the duodenum.

conclusionsWe report a rare case of a giant pancreatic-type ACC of the duodenum, which was strongly suspected to have arisen from ectopic pancreatic tissue. This case highlights the diagnostic challenges associated with pancreatic-type ACC of the duodenum and adds valuable information to the limited literature on this rare entity.

Indexed as

acinar cell carcinomaduodenumectopic pancreas

Identifiers

PMID41426523
PMCPMC12714493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.