Evidence map›Paper›PMID 41426371›Full record

ArticlePediatric investigation2025

A 15-year population-based study on incidence and vaccination coverage in pediatric inflammatory bowel disease in Italy.

Francesca Fortunato, Angelo Campanozzi, Michele Di Toma, Alessandra Marinari, Domenico Martinelli

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In one paragraph

Article in Pediatric investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca FortunatoDepartment of Medical and Surgical Sciences Hygiene Unit University of Foggia Foggia Italy.ORCID https://orcid.org/0000-0003-0665-5385
Angelo CampanozziDepartment of Medical and Surgical Sciences Pediatrics Unit University of Foggia Foggia Italy.
Michele Di TomaDepartment of Pediatrics Policlinico Foggia Hospital Foggia Italy.
Alessandra MarinariDepartment of Pediatrics Policlinico Foggia Hospital Foggia Italy.
Domenico MartinelliDepartment of Medical and Surgical Sciences Hygiene Unit University of Foggia Foggia Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: The incidence of pediatric inflammatory bowel disease (IBD) is increasing worldwide, particularly after the coronavirus disease 2019 pandemic. As children with IBD are at higher risk of infection, adherence to vaccination schedules is essential. However, data on the incidence of IBD and vaccination coverage in Italian children remain limited. Objective: To assess the incidence of IBD in children aged 0-14 years in the Apulia region of Italy (2009-2023) and to evaluate their vaccination coverage for both mandatory and recommended vaccines. Methods: A retrospective population-based study was conducted using hospital discharge records and a user fee exemption registry to identify incident IBD cases. Vaccination history was obtained from the regional immunization system. Age-standardized incidence rates (SIRs) were calculated. Vaccination coverage was assessed based on the receipt of all age-appropriate vaccines according to regional immunization schedules. Results: Between 2009 and 2023, 1044 incident pediatric IBD cases were identified, with an average annual SIR of 12.7/100 000. A significant increase in incidence occurred after 2020 ( Interpretation: The incidence of pediatric IBD is increasing in Apulia, whereas vaccination coverage remains below optimal levels. Targeted strategies are needed to enhance immunization in this vulnerable population.

Indexed as

Crohn's diseaseIncidenceInflammatory bowel diseasePediatricsUlcerative colitisVaccination coverage

Identifiers

PMID41426371
PMCPMC12715895

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.