Evidence map›Paper›PMID 41426149›Full record

ArticleSouth Asian journal of cancer2025

Induction versus Adjuvant Chemotherapy Combined with Concurrent Chemoradiation: What Is Beneficial in Locally Advanced Nasopharyngeal Carcinoma-A 5-Year Comparative Study at a Tertiary Care Center in North India.

Kaneez Fatima, Asifa Andleeb, Shahida Nasreen, Mushtaq Ahmad Sofi, Ulfat Ara Wani, Malik Tariq Rasool, Arshad Manzoor Najmi, Shaqul Qamar, Nazir Ahmad, Rubiya Ryhan

Abstract read
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In one paragraph

Article in South Asian journal of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kaneez FatimaDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.ORCID 0000-0002-2449-6317
Asifa AndleebDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Shahida NasreenDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.ORCID 0009-0000-0481-9775
Mushtaq Ahmad SofiDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Ulfat Ara WaniDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Malik Tariq RasoolDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Arshad Manzoor NajmiDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Shaqul QamarDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Nazir AhmadDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.
Rubiya RyhanDepartment of Radiation Oncology, Medical Oncology, Sheri Kashmir Institute of Medical Sciences (SKIMS), Soura UT, Jammu and Kashmir, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In locally advanced nasopharyngeal cancer (LANPC), concurrent chemoradiotherapy (CCRT) has been established as the current standard of care, but recently, the addition of induction chemotherapy to CCRT has presented an attractive multidisciplinary approach. Objectives: The aim of the study was to explore the clinical outcome of induction chemotherapy (IC) followed by CCRT and CCRT followed by adjuvant chemotherapy (AC) in LANPC. Material and Methods: In this propensity score-matched retrospective cohort study, we enrolled LANPC patients from October 2016 to June 2022. Study variables were evenly distributed by propensity score matching. Independent prognostic factors were identified using Cox regression analysis, and the outcome between the two chemotherapy treatment combinations was compared for patients in different subgroups. Result: A total of 80 patients were included in the study. Survival outcomes indicated that the IC followed by CCRT group (IC + CCRT) achieved a higher 5-year overall survival (OS; 90 vs. 81%, Conclusion: In patients with LANPC, especially with T3 or N2 disease, IC should be strongly considered followed by CCRT.

Indexed as

adjuvant chemotherapychemoradiationinduction chemotherapylocally advanced nasopharyngeal carcinoma

Identifiers

PMID41426149
PMCPMC12714473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.