Evidence map›Paper›PMID 41426120›Full record

ArticleNanophotonics (Berlin, Germany)2025

High-sensitivity U-shaped biosensor for rabbit IgG detection based on PDA/AuNPs/PDA sandwich structure.

Pengxiang Chang, Yirui Zhang, Ailing Zhang, Zhen Li, Zhiyang Wang, Yanmei Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanophotonics (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pengxiang ChangTianjin Key Laboratory of Thin Film Electronics and Communication Devices, Engineering Research Center of Optoelectronic Devices and Communication Technology, Ministry of Education, College of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.
Yirui ZhangTianjin Key Laboratory of Thin Film Electronics and Communication Devices, Engineering Research Center of Optoelectronic Devices and Communication Technology, Ministry of Education, College of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.
Ailing ZhangTianjin Key Laboratory of Thin Film Electronics and Communication Devices, Engineering Research Center of Optoelectronic Devices and Communication Technology, Ministry of Education, College of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.ORCID https://orcid.org/0000-0002-8061-1682
Zhen LiTianjin Key Laboratory of Thin Film Electronics and Communication Devices, Engineering Research Center of Optoelectronic Devices and Communication Technology, Ministry of Education, College of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.
Zhiyang WangTianjin Key Laboratory of Thin Film Electronics and Communication Devices, Engineering Research Center of Optoelectronic Devices and Communication Technology, Ministry of Education, College of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.
Yanmei ShiTianjin Key Laboratory of Thin Film Electronics and Communication Devices, Engineering Research Center of Optoelectronic Devices and Communication Technology, Ministry of Education, College of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combining the advantages of polydopamine (PDA), gold nanoparticles (AuNPs), and U-shaped optical fibers, a PDA/AuNPs/PDA sandwich structure modified U-shaped optical fiber surface plasmon resonance (SPR) biosensor was proposed and used for the detection of rabbit IgG. The U-shaped structure significantly enhances the penetration depth of the evanescent field. The PDA/AuNPs/PDA sandwich structure boosts coupling efficiency of SPR and LSPR, increases the specific surface area of the sensor, and improves surface activity. The experimental results show that the refractive index (RI) sensitivity of the sensor is 6,206.32 nm/RIU in the RI range of 1.3353-1.3595, which is 1.63 times higher than the raw U-shaped sensor. The biosensor for detection of rabbit IgG achieved a biosensitivity of 0.153 nm/(ng/mL), which is two orders of magnitude higher and a limit of detection (LOD) of 0.131 ng/mL, which is one order of magnitude lower. The outstanding performance of the proposed biosensor offers a new solution for the detection of low-concentration biological solutions, and it has great potential applications in the field of medical diagnosis.

Indexed as

biosensorgold nanoparticlespolydopaminerabbit IgGsurface plasmon resonanceU-shaped

Identifiers

PMID41426120
PMCPMC12717939

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.