Evidence map›Paper›PMID 41426042›Full record

ArticleKidney international reports2025

Effect of Baseline Dialysis and Plasma Exchange on Renal Prognosis in Patients With Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.

Maxime Vignac, Dorian Nezam, François Grolleau, Pauline Morel, Dimitri Titeca-Beauport, Stanislas Faguer, Alexandre Karras, Justine Solignac, Noémie Jourde-Chiche, François Maurier and 42 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

52 authors.

Maxime VignacService de Médecine Interne, Hôpital Cochin, Université Paris Cité, Paris, France.
Dorian NezamService de Néphrologie, Dialyse et Transplantation, CHU de Rouen, France.
François GrolleauCentre de Recherche épidémiologie et Statistiques, Université de Paris, Paris, France.
Pauline MorelService de dialyse et aphérèse, AURA Paris Plaisance, Paris, France.
Dimitri Titeca-BeauportService de Néphrologie, CHU Amiens Picardie, Amiens, France.
Stanislas FaguerDépartement de Néphrologie et Transplantation d'organes, Hôpital Rangueil, Toulouse, France.
Alexandre KarrasService de Néphrologie, Hôpital Européen Georges Pompidou, Université de Paris, Paris, France.
Justine SolignacCentre de Néphrologie et Transplantation Rénale, Hôpital de la Conception (APHM), Marseille, France.
Noémie Jourde-ChicheCentre de Néphrologie et Transplantation Rénale, Hôpital de la Conception (APHM), Marseille, France.
François MaurierHôpital Belle-Isle, Groupe Hospitalier Associatif UNEOS, Metz, France.
Hamza SakhiService de Néphrologie et Transplantation, Centre de référence Maladie rare Syndrome Néphrotique Idiopathique, Hôpitaux Universitaires Henri Mondor, Créteil, France.
Khalil El KarouiUnité de Néphrologie, Transplantation Rénale, Hôpital Tenon (Assistance Publique des Hôpitaux de Paris), Paris, France.
Rafik MesbahService de Néphrologie, Centre Hospitalier, Boulogne-sur-mer, France.
Pierre Louis CarronService de Néphrologie, Hôpital Nord, CHU Grenoble, Grenoble, France.
Vincent AudardService de Néphrologie et Transplantation, Centre de référence Maladie rare Syndrome Néphrotique Idiopathique, Hôpitaux Universitaires Henri Mondor, Créteil, France.
Didier DuclouxService de Néphrologie, Dialyse et Transplantation, CHU Besançon, France.
Romain PauleService de Médecine Interne, Hôpital Foch, Suresnes, France.
Jean-François AugustoService de Néphrologie, Dialyse, Transplantation, CHU, CHU Angers, Angers, France.
Julien AniortService de Néphrologie, Dialyse et Transplantation rénale, CHU Gabriel Montpied, Clermont-Ferrand, France.
Aurélien TipleService de Néphrologie, CHU Jacques Lacarin, Vichy, France.
Cédric RafatUnité de Néphrologie, Transplantation Rénale, Hôpital Tenon (Assistance Publique des Hôpitaux de Paris), Paris, France.
Séverine BeaudreuilService de Néphrologie, Dialyse et Transplantation rénale, Hôpital Bicêtre, Le Kremlin Bicêtre, France.
Xavier PuéchalService de Médecine Interne, Hôpital Cochin, Université Paris Cité, Paris, France.
Pierre GobertService de Médecine interne, Centre hospitalier Carpentras, Carpentras, France.
Ziad MassyDépartement de Néphrologie, Hôpital Ambroise Paré, Boulogne Billancourt, France.
Catherine HanrotelService de Néphrologie, Dialyse et Transplantation rénale, Hôpital La Cavale Blanche, Brest, France.
Stéphane BallyService de Néphrologie Dialyse, Centre Hospitalier Métropole Savoie, Chambery, France.
Nihal MartisService de Médecine Interne, CHU Nice, Nice, France.
Cécile-Audrey DurelService de Médecine Interne, Hôpital Saint Joseph Saint Luc, Lyon, France.
Geoffroy DesbuissonsService de Néphrologie, Hôpitaux Privés de l'ouest Parisien, Trappes, France.
Pascal GodmerService de Médecine Interne, CHBA site de Vannes, Vannes, France.
Aurélie HummelService de Néphrologie et Transplantation Rénale, Hôpital Necker-Enfants Malades (Assistance Publique des Hôpitaux de Paris), Paris, France.
François PerrinService de Médecine Interne, CHU de Saint-Nazaire, France.
Antoine NéelService de Médecine Interne, CHU de Nantes, Nantes, France.
Claire De MoreuilService de Médecine Interne, CHRU de Brest, Brest, France.
Tiphaine GoulenokService de Médecine Interne, Hôpital Bichat (Assistance Publique des Hôpitaux de Paris), Paris, France.
Dominique GuerrotService de Néphrologie, CIC-CRB 1404, INSERM EnVi U1096, CHU Rouen, Rouen, France.
Steven GrangeService de Réanimation médicale, CHU Charles Nicolle, Rouen, France.
Aurélie FoucherService de Médecine Interne, CHU site Sud Saint-Pierre, Saint-Pierre, France.
Alban DerouxService de Médecine Interne, CHU de Grenoble, Grenoble, France.
Alexandra DervauxService d'anatomie et de cytologie pathologiques, Hôpital Nord, CHU d'Amiens, France.
Céline Guilbeau-FrugierService d'anatomie pathologique et histologie-cytologie, Hôpital de Rangueil-Larrey, CHU Toulouse, Toulouse, France.
Anne Modesto-SegondsService d'anatomie pathologique et histologie-cytologie, Hôpital de Rangueil-Larrey, CHU Toulouse, Toulouse, France.
Dominique NochyService d'Anatomie et Cytologie Pathologiques, Hôpital Européen Georges Pompidou (Assistance Publique des Hôpitaux de Paris), Paris, France.
Laurent DanielService d'Anatomie et cytologie pathologiques, Hôpital La Timone (APHM), Marseille, France.
Anissa MoktefiAssistance Publique des Hôpitaux de Paris, Department of Pathology, Groupe Hospitalier Henri-Mondor, Créteil, France.
Marion RabantDepartment of Pathology, Necker Hospital, Assistance Publique des Hôpitaux de Paris, Paris, France.
Loïc GuillevinService de Médecine Interne, Hôpital Cochin, Université Paris Cité, Paris, France.
Alexis RégentService de Médecine Interne, Hôpital Cochin, Université Paris Cité, Paris, France.
Raphaël PorcherCentre de Recherche épidémiologie et Statistiques, Université de Paris, Paris, France.
Benjamin TerrierService de Médecine Interne, Hôpital Cochin, Université Paris Cité, Paris, France.
French Vasculitis Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The identification of prognostic factors for renal failure in antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) remains a challenge. The benefit of plasma exchange (PLEX) has been questioned, and the target population remains to be defined. We investigated the outcome of patients requiring renal replacement therapy (RRT) at baseline and factors associated with their prognosis at 1 year. Methods: This retrospective multicenter study evaluated the 1-year composite end point of death or end-stage kidney disease (ESKD) in patients with biopsy-proven renal AAV involvement. Results: Of the 394 patients included, 105 (26.6%) were on dialysis at baseline. Of these, 60 (57.1%) reached the composite end point compared with 29 patients (10.0%) who were not on RRT at baseline ( Conclusion: MPO-ANCA, need for dialysis, and high histological renal risk score at baseline were associated with the 1-year composite end point of death or ESKD. Almost half of the patients on dialysis at baseline were off dialysis at 1 year, with a better prognosis in those who had received PLEX.

Indexed as

ANCAhemodialysisplasmapheresisvasculitis

Identifiers

PMID41426042
PMCPMC12712459

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