Evidence map›Paper›PMID 41426004›Full record

ArticleACS nanoscience Au2025

Ultrabright NIR-II Nanoprobes for

Isabella Vasquez, Asma Harun, Robert Posey, Ruhan Reddy, Nikita Gill, Ulrich Bickel, Joshua Tropp, Indrajit Srivastava

Abstract read
In one paragraph

Article in ACS nanoscience Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isabella VasquezDepartment of Mechanical Engineering, Edward E. Whitacre Jr. College of Engineering, Texas Tech University, Lubbock, Texas 79409, United States.ORCID https://orcid.org/0009-0003-4242-0521
Asma HarunDepartment of Mechanical Engineering, Edward E. Whitacre Jr. College of Engineering, Texas Tech University, Lubbock, Texas 79409, United States.
Robert PoseyDepartment of Chemistry & Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Ruhan ReddyDepartment of Mechanical Engineering, Edward E. Whitacre Jr. College of Engineering, Texas Tech University, Lubbock, Texas 79409, United States.ORCID https://orcid.org/0009-0004-9713-0262
Nikita GillDepartment of Chemistry & Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Ulrich BickelTexas Center for Comparative Cancer Research (TC3R), Amarillo, Texas 79106, United States.
Joshua TroppDepartment of Chemistry & Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.ORCID https://orcid.org/0000-0002-1427-1296
Indrajit SrivastavaDepartment of Mechanical Engineering, Edward E. Whitacre Jr. College of Engineering, Texas Tech University, Lubbock, Texas 79409, United States.ORCID https://orcid.org/0000-0002-6864-0202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared (NIR) fluorescence imaging is a powerful, noninvasive tool for cancer diagnosis, enabling real-time, high-resolution visualization of biological systems. While most probes target the first NIR window (NIR-I, 700-900 nm), recent advances focus on the second window (NIR-II, 1000-1700 nm), which offers deeper tissue penetration and reduced interference from scattering and autofluorescence. However, many current NIR-II nanoprobes show suboptimal brightness and limited validation in more human-centric models. Here, we present an orthogonal strategy combining molecular engineering, by modulating the amount and position of thiophene moieties in semiconducting polymers (SPs), with protein nanoengineering to develop ultrabright NIR-II imaging probes optimized for

Indexed as

bioimagingbovine serum albuminmolecular engineeringnanoengineeringNIR-IIsemiconducting polymer nanoparticles

Identifiers

PMID41426004
PMCPMC12715628

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.