Evidence map›Paper›PMID 41425999›Full record

ArticleACS nanoscience Au2025

Enhancing Gene Delivery and Immune Modulation in Primary Dendritic Cells by Utilizing Composites of Iron Oxide Nanocubes and Biocompatible PLGA-PDMAEMA Polymers.

Chonnavee Manipuntee, Chalathan Saengruengrit, Kasirapat Ariya-Anandech, Warerat Kaewduangduen, Areerat Kunanopparat, Amanee Samaeng, Asada Leelahavanichkul, Patcharee Ritprajak, Numpon Insin

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In one paragraph

Article in ACS nanoscience Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chonnavee ManipunteeDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Chalathan SaengruengritDepartment of Medical Sciences, Ministry of Public Health, Bureau of Quality and Safety of Food, Nonthaburi 11000, Thailand.
Kasirapat Ariya-AnandechCenter of Excellence in Integrative Immuno-Microbial Biochemistry and Bioresponsive Nanomaterials, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Warerat KaewduangduenCenter of Excellence in Integrative Immuno-Microbial Biochemistry and Bioresponsive Nanomaterials, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Areerat KunanopparatCenter of Excellence in Integrative Immuno-Microbial Biochemistry and Bioresponsive Nanomaterials, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Amanee SamaengCenter of Excellence in Integrative Immuno-Microbial Biochemistry and Bioresponsive Nanomaterials, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Asada LeelahavanichkulCenter of Excellence in Translational Research in Inflammation and Immunology (CETRII), Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Patcharee RitprajakCenter of Excellence in Integrative Immuno-Microbial Biochemistry and Bioresponsive Nanomaterials, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.ORCID https://orcid.org/0000-0003-1392-4061
Numpon InsinDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID https://orcid.org/0000-0002-7307-5439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) represent pivotal targets in immunotherapy, gene therapy, and vaccine delivery for major diseases including cancer, autoimmune diseases, and transplant rejection. Overcoming the challenge of efficient gene delivery via conventional nonviral molecules into primary DCs has been a persistent obstacle. Within this research, we introduce an innovative gene delivery system utilizing magnetic iron oxide nanocubes (MCs) encapsulated with a biocompatible polymer, poly-(lactic-

Indexed as

dendritic cellDNA plasmidgene deliverymagnetic iron oxide nanocubessuperparamagnetictransfection efficiency

Identifiers

PMID41425999
PMCPMC12715624

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.