Evidence map›Paper›PMID 41425967›Full record

ArticleFrontiers in cellular and infection microbiology2025

Post-COVID-19 era pathogen profiles and influencing factors for hospital patients with lower respiratory tract infections in Shenzhen, China.

Tong Li, Dandan Niu, Yingluan Zhang, Renli Zhang, Yongchao Guo, Tengyingzi Liu, Dana Huang, Zhen Zhang, Zhanhong Rao, Xiaolu Shi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tong LiShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Dandan NiuShenzhen Uni-medical Technology Co., Ltd, Shenzhen, China.
Yingluan ZhangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Renli ZhangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Yongchao GuoShenzhen Research Center for Communicable Disease Control and Prevention, Chinese Academy of Medical Sciences, Shenzhen, China.
Tengyingzi LiuShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Dana HuangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Zhen ZhangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Zhanhong RaoBao'an District Center for Disease Control and Prevention, Shenzhen, China.
Xiaolu ShiShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Xiaomin ZhangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Tiejian FengShenzhen Center for Disease Control and Prevention, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lower respiratory tract infections (LRTIs) are associated with significant morbidity, hospitalizations, and mortality globally. The aim of this study was to investigate the causative pathogens and epidemiological characteristics of LRTIs including the factors influencing the severity of illness and the length of hospital stay (LOS). Methods: From November 2023 to June 2024, a prospective study including 121 patients was performed at four hospitals in Shenzhen, China. The bronchoalveolar lavage fluid (BALF) samples from inpatients with LRTIs were strictly collected and tested using targeted next-generation sequencing (tNGS). A total of 108 respiratory pathogens were included in the detection list. Results: Of the total inpatients, 89.3% tested positive for one or more pathogens (108/121). The three leading pathogens were Conclusions: Different age groups of hospitalized patients showed different pathogen profiles and types of co-infection, indicating the significance of age-targeted clinical medical practice. The most common pathogens that caused LRTIs were

Indexed as

COVID-19Respiratory Tract InfectionsAdultAgedAged, 80 and overAge FactorsBronchoalveolar Lavage FluidChinaCoinfectionFemaleHaemophilus influenzaeHigh-Throughput Nucleotide SequencingHospitalizationHumansLength of StayMalebronchoalveolar lavage fluidetiologylower respiratory tract infectionstargeted next-generation sequencingthe length of hospital stay

Identifiers

PMID41425967
PMCPMC12714876

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.