ArticleFrontiers in microbiology2025
Host sweet preference modulates the salivary microbiome and its divergent associations with plaque-associated and non-plaque-related oral diseases.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Microorganisms play a critical role in the progression of oral diseases. However, it remains unclear whether the frequency of sweet consumption influences the salivary microbiota in both plaque-associated and non-plaque-related oral diseases. Methods: Based on salivary microbiome analysis, unstimulated saliva samples were collected from university students aged 17-20, including healthy controls (HC), dental caries (DC), and dental fluorosis (DF) groups, under different sweet consumption frequencies. Microbiota potentially critical in disease development were identified. Results: No significant differences in α- and β-diversity were observed among the three groups. However, distinct microbial structures at the genus and species levels were evident under different sweet consumption conditions. Under high sweet consumption, the caries group exhibited enrichment of microbiota closely associated with sugar metabolism and acid production (e.g.,
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