ArticleFrontiers in microbiology2025
Metabolomic analysis of
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pneumococcal infection, caused by Methods: In this study, twenty serum samples from individuals infected with Results: Through comparative analysis of the metabolic profiles of infected individuals and normal controls, we identified 418 metabolites that significantly contributed to the differentiation of group samples. The identified metabolites were categorized into various groups, such as amino acids, fatty acids, and phosphatidylcholine, and were enriched in pathways including galactose metabolism, the hypoxia-inducible factor-1 (HIF-1) signaling pathway, the citrate cycle, the pentose phosphate pathway, and glycolysis/gluconeogenesis. Conclusion: Our study provides a comprehensive and real-time analysis of the metabolic network, elucidating the complex processes that occur following pathogen invasion in the human body. The identification of metabolic biomarkers and enriched pathways lays a foundational framework for research and offers visualizable targets for the diagnosis and treatment of pneumococcal infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.