SynthesisFrontiers in psychiatry2025
Exploring the global prevalence of mood and anxiety disorders in LGBTIQ+ people: A systematic review.
Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- How much is sexual minority stress confounded with familial causes? A systematic multilevel meta-analysis.Psychological medicine · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The prevalence of mood and anxiety disorders in LGBTIQ+ individuals (lesbian, gay, bisexual, transgender, intersex, queer, and other sexual/gender minorities) is not well understood. Studies suggest that LGBTIQ+ people may have higher rates of mood and anxiety disorders, potentially influenced by societal acceptance. Aims: This systematic review aims to examine the prevalence of depressive disorders (DD), bipolar disorders (BD), and anxiety disorders in LGBTIQ+ populations and explore potential associations with societal acceptance in different global regions. Methods: A systematic search of PubMed, Embase, APA PsychInfo, and citations from 1990-2022 identified studies reporting on the prevalence of DD, BD, and anxiety disorders among LGBTIQ+ people. These rates were compared to societal acceptance, using the Williams' Institute Global Acceptance Index, and to general population rates. Study quality was assessed with the National Institute of Health checklist. Results: 123 studies from 31 countries were included, with 116 rated as good quality. Individual study sample sizes ranged from 15 to over 254,462,596. Mean prevalence rates in LGBTIQ+ populations from these studies was 35.3% for depressive disorders, 5.6% for bipolar disorders, and 34.3% for anxiety disorders. A significant correlation was found between societal acceptance and depressive and anxiety disorder prevalence rates in North American LGBTIQ+ populations. Conclusions: This study found that LGBTIQ+ people experience markedly higher rates of mood and anxiety disorders compared to the general population, with societal acceptance correlating with these rates in North America. Further research is needed, particularly for underrepresented groups such as nonbinary individuals and those identifying as pansexual, asexual, or genderqueer. Systematic review registration: www.crd.york.ac.uk/prospero/, identifier CRD42022320324.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.