Evidence map›Paper›PMID 41425810›Full record

ReviewFrontiers in psychiatry2025

Neurofeedback in substance and non substance-related addictions: a mini review of current evidence and future directions.

Bruna Sanader Vukadinovic

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bruna Sanader VukadinovicUniversity College London Hospitals NHS Foundation Trust, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurofeedback (NF) is emerging as a promising adjunctive intervention for substance use disorders (SUDs) and behavioral addictions. By providing real-time feedback on brain activity, NF enables individuals to self-regulate neural circuits implicated in craving, reward processing, and executive control. This mini review synthesizes recent evidence regarding the efficacy, mechanisms, and clinical applications of NF in addiction treatment. Addiction remains a major public health concern characterized by high relapse rates and limited long-term success from pharmacological and psychosocial therapies, underscoring the need for innovative approaches. Studies included in this review were identified through PubMed, Scopus, and Web of Science using the terms "neurofeedback," "EEG," "fMRI," "addiction," "substance use disorder," "behavioral addiction," and "craving," with priority given to publications from 2019-2025. Two primary NF modalities have been examined: electroencephalography (EEG)-based and functional magnetic resonance imaging (fMRI)-based neurofeedback. EEG-NF, particularly the alpha-theta protocol, has demonstrated reductions in craving, anxiety, and relapse rates among individuals with alcohol and substance dependence. fMRI-NF enables targeted modulation of addiction-related brain regions, such as the insula and dorsolateral prefrontal cortex, with region-specific but variable clinical effects. Systematic reviews indicate that NF, especially EEG-based, reliably reduces craving and improves psychological outcomes, though methodological heterogeneity limits generalizability. Recent advances integrating NF with biofeedback and machine learning approaches suggest potential for personalized and multimodal interventions. Overall, NF represents a promising, neuroscience-informed adjunct in addiction treatment, warranting large-scale controlled trials to establish efficacy and optimize clinical application.

Indexed as

addictionbehavioral addictioncravingEEGfMRIneurofeedbacksubstance use disorder

Identifiers

PMID41425810
PMCPMC12711497

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.