Evidence map›Paper›PMID 41425781›Full record

ReviewCJC open2025

A Systematic Review of the Prognostic Value of Cardiopulmonary Exercise Testing in Patients with Ischemic and Nonischemic Cardiomyopathy.

Holden Lowes, Ingrid Brenner, Kirsten Woodend, Sarah West, Manjot Sunner, Barinder Khehra, Ani Orchanian-Cheff, Juan Jose Rodriguez Arias, Farid Foroutan, Chun Po S Fan and 4 more

Abstract readReview
In one paragraph

Review in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Holden LowesEnvironmental and Life Sciences, Trent University, Peterborough, Ontario, Canada.
Ingrid BrennerEnvironmental and Life Sciences, Trent University, Peterborough, Ontario, Canada.
Kirsten WoodendEnvironmental and Life Sciences, Trent University, Peterborough, Ontario, Canada.
Sarah WestEnvironmental and Life Sciences, Trent University, Peterborough, Ontario, Canada.
Manjot SunnerTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Barinder KhehraTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Ani Orchanian-CheffTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Juan Jose Rodriguez AriasTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Farid ForoutanTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Chun Po S FanTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Eduard Rodenas-AlesinaTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Juan Duero PosadaTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Heather J RossTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Yasbanoo MoayediTed Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prognostic utility of cardiopulmonary exercise testing (CPET) in heart failure (HF) is well established; however, whether optimal CPET parameter thresholds differ across HF etiologies remains unclear. This systematic review aimed to determine how CPET-derived parameters and their prognostic threshold values differ, and their association with adverse outcomes, in patients with ischemic vs nonischemic cardiomyopathy. Methods: Eligible studies assessed adult HF patients and reported outcomes of all-cause mortality, left ventricular assist device implantation, heart transplantation, or hospitalization. CPET parameters and associated threshold values were extracted, and risk of bias was assessed using the Joanna Briggs Institute checklist for cohort studies. Results: Four studies comprising 491 ischemic and 218 nonischemic HF patients were included. Peak oxygen consumption (pVO Conclusions: Significant heterogeneity was present in study design, patient populations, and CPET variables assessed. The few consistently assessed prognostic thresholds were similar across HF etiologies. Peak oxygen consumption (pVO

Indexed as

Cardiopulmonary exercise testingheart failureischemic cardiomyopathynonischemic cardiomyopathyprognosis

Identifiers

PMID41425781
PMCPMC12713171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.