ArticleClinical ophthalmology (Auckland, N.Z.)2025
Quantitative Anterior Segment SD-OCT Assessment of the Iridocorneal Angle in Chinese Patients with Open-Angle Glaucoma or Ocular Hypertension: An Observational Study.
Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: We evaluated iridocorneal angle biometrics using anterior segment spectral-domain optical coherence tomography (SD-OCT) compared with Shaffer grade clinical assessments in Chinese patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) to determine which method is most suitable for preoperative angle assessment. Methods: This noninterventional, prospective study enrolled 206 patients with OAG or OHT in both eyes and Shaffer grade >1 iridocorneal angles at 3 sites in China. Shaffer grades and SD-OCT 5-line raster scans (Zeiss Cirrus HD-OCT 4000) of the inferior angle were obtained under dark conditions. Images were evaluated for visualization of Schwalbe's line, the superior iris surface, and angle recess. ImageJ software was used to measure the angle-opening distance at Schwalbe's line (SL-AOD) in gradable images. Results: Almost all study eyes had Shaffer grade 4 (91.0%) or grade 3 (8.3%) angles. Mean (standard deviation) SL-AOD was 0.75 (0.33) mm (median 0.73, range 0.051-1.9, n=322). The SL-AOD was <0.635 mm (the tube outer diameter of the Ahmed glaucoma valve and Baerveldt glaucoma implant) in 37.6% of the eyes. SL-AOD values did not differ significantly between OAG and OHT diagnoses or between phakic and pseudophakic eyes. Conclusion: Iridocorneal angle biometrics derived from SD-OCT images in Chinese patients with OAG or OHT showed large variation in the SL-AOD in eyes with open angles on gonioscopy. Over one-third of patients had SL-AOD too small to safely accommodate commonly used glaucoma tube shunts. Expanded preoperative use of SD-OCT could potentially be beneficial to detect angles at risk for corneal complications and inform device selection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.