ReviewNational science review2025
Molecular tools for decoding multicellular systems: from mechanisms to medicine.
Review in National science review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Thiol-Retaining N-Terminal Cysteine Chemistry for Dual Modification and Bicyclic Peptide Construction.Journal of the American Chemical Society · 2026Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell-cell communication (CCC) is fundamental to essential biological processes including growth, differentiation, immune surveillance, and tissue homeostasis, and its dysregulation underlies various diseases such as cancer, autoimmunity, and neurodegeneration. In response to growing interest in decoding complex multicellular interactions, the 380th Shuangqing Forum entitled 'Chemical, Biological, and Medical Frontiers in Multicellular Complex Systems' was convened, providing a platform to discuss recent interdisciplinary breakthroughs. This review, emerging from forum discussions, highlights the latest advancements in molecular tools-such as super-resolution imaging, proximity labeling, bioorthogonal chemistry, synthetic receptors, and single-cell spatial omics-that enable unprecedented insights into spatial, molecular, and functional aspects of CCC. Emphasizing their translational potential, we discuss their profound implications for immuno-oncology, regenerative medicine, and autoimmune diseases. We further outline current challenges and opportunities, particularly advocating for a future precision medicine framework centered around targeted modulation of cell-cell interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.