ArticleDepression and anxiety2025
Study on the Changes of Brain Function in Adolescents With Pain-Depression Comorbidity Based on rs-FMRI.
Article in Depression and anxiety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Identification of susceptibility modules and genes through WGCNA and ceRNA network analysis in neuropathic pain-induced anxiodepression.Translational psychiatry · 2026Article
- Study on the Changes of Brain Function in Adolescents With Pain-Depression Comorbidity Based on rs-FMRI.Depression and anxiety · 2025Article
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7 authors.
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Abstract
Background: The underlying mechanism of pain-depression comorbidity is not well understood. This study aims to analyze the abnormal brain activity in adolescents with pain-depression comorbidity, and to provide imaging evidence for the understanding of brain neural mechanisms of pain-depression comorbidity. Methods: Depression in adolescents with ( Results: Compared with the depression group, the comorbidity group showed increased ALFF values in the right amygdala and right middle frontal gyrus, decreased ALFF values in the left middle occipital gyrus, right inferior temporal gyrus and right superior temporal gyrus, increased ReHo values in the right insula, and elevated functional connectivity between the right inferior temporal gyrus and right angular gyrus (Gaussian random field [GRF] corrected, Conclusion: Compared with adolescents with depression without pain, adolescents with pain-depression comorbidity have differences in neuronal activity and functional connectivity in the middle frontal gyrus, amygdala, insular lobe, temporoparietal and occipital lobes, suggesting that abnormal neuronal activity in these brain regions may be the neural basis of pain-depression comorbidity.
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