Evidence map›Paper›PMID 41425562›Full record

ReviewFrontiers in immunology2025

Viral manipulation of the HLA class I antigen processing and presentation pathway.

Dominic S Nolan, Arwen F Altenburg

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dominic S NolanDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
Arwen F AltenburgDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major histocompatibility complex (MHC, human leukocyte antigen [HLA] in humans) class I molecules present peptides at the cell surface to cytotoxic immune cells. Peptides are generated and selected for MHC class I presentation in the antigen processing and presentation (APP) pathway. Recognition of a foreign peptide in the context of MHC class I by CD8

Indexed as

Antigen PresentationHistocompatibility Antigens Class IVirus DiseasesVirusesAnimalsCD8-Positive T-LymphocytesHumansHistocompatibility Antigens Class Iantigen presentationCD8+ T cellsHLAimmune evasioninfectionMHCNK cellsvirus

Identifiers

PMID41425562
PMCPMC12714902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.