Evidence map›Paper›PMID 41425435›Full record

ArticleAnnals of thoracic surgery short reports2025

Aortic Root Replacement in Patients With Ventricular Septal Defect.

Ryota Takahashi, Hiroshi Munakata, Kenji Okada, Taro Hayashi, Tatsuichiro Seto, Hisao Suda, Yutaka Okita

Abstract read
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Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Ryota TakahashiTakatsuki General Hospital, Osaka, Japan.
Hiroshi MunakataOkinawa Southern Medical Center, Okinawa, Japan.
Kenji OkadaKobe University, Kobe, Japan.
Taro HayashiAkashi Medical Center, Akashi, Japan.
Tatsuichiro SetoShinshu University, Matsumoto, Japan.
Hisao SudaNagoya City University, Nagoya, Japan.
Yutaka OkitaTakatsuki General Hospital, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aortic root replacement in patients with ventricular septal defect (VSD) requires a modified surgical technique. Methods: Between 2000 and 2022, 12 patients with aortic regurgitation and VSD underwent an operation. Their age at operation was 31.8 (SD 19.9) years. The VSD was patent in 5 patients and spontaneously or surgically closed in 7 patients. The location of the VSD was subarterial in 6 patients, perimembranous in 5, and muscular in 1 patient. The aortic valve was tricuspid in 8 patients, bicuspid in 2, and unicuspid in 2. Eight patients also had annuloaortic ectasia. Results: The VSDs were closed using a patch in 4 patients and directly closed in 1 patient. The aortic root procedures were valve-sparing reimplantation in 7 patients, root remodeling in 1, basal ring annuloplasty in 1, basal ring annuloplasty with sinutubular junction annuloplasty in 1, and a Ross procedure in 1 patient. Additional cusp repair was required in 9 patients. No early deaths occurred. The postoperative follow-up periods were 5.3 (3.4) years. Two patients died, and 1 underwent aortic valve replacement 4 years postoperatively. Survival was 91.7 (8.0)% at 5 years and 68.8 (20.7)% at 10 years. Freedom from aortic valve reoperation was 88.9 (10.5)% at 10 years. Conclusions: Valve-sparing root reimplantation in patients with annuloaortic ectasia and VSD may require a special first row suture line. Patients with prolapsed cusps may require resuspension or cusp extension. The Ross operation can be an alternative for patients with severely deformed aortic cusps.

Identifiers

PMID41425435
PMCPMC12712189

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