Evidence map›Paper›PMID 41425380›Full record

ArticleAnnals of thoracic surgery short reports2025

Too Hot? Don't Believe Me, Just Watch: Highly Positron Emission Tomography-Avid Thoracic Schwannomas.

Neelesh Bagrodia, Peter J Kneuertz, Nicholas J Pastis, Desmond M D'Souza, Robert E Merritt, Ioana Baiu

Abstract readCase Reports
In one paragraph

Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Neelesh BagrodiaThe Ohio State University Wexner Medical Center, Columbus, Ohio.
Peter J KneuertzThe Ohio State University Wexner Medical Center, Columbus, Ohio.
Nicholas J PastisDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Desmond M D'SouzaThe Ohio State University Wexner Medical Center, Columbus, Ohio.
Robert E MerrittThe Ohio State University Wexner Medical Center, Columbus, Ohio.
Ioana BaiuThe Ohio State University Wexner Medical Center, Columbus, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schwannomas are benign peripheral nerve sheath tumors with characteristic imaging features and low avidity on positron emission tomography (PET). Transformation into malignant peripheral nerve sheath tumors (MPNSTs) is rare (<0.3%), but it typically manifests with invasive, large (>5 cm), PET-avid, heterogeneous tumors. Although schwannomas may be monitored or excised, MPNSTs require aggressive systemic treatment. We present 2 intrathoracic schwannomas with discordant radiologic and pathologic findings, highlighting the preoperative diagnostic uncertainty. These cases emphasize the critical role of multidisciplinary evaluation in guiding management when high PET avidity suggests malignancy despite benign pathologic features.

Identifiers

PMID41425380
PMCPMC12712141

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.