ArticleACS measurement science au2025
Cooperative Split DNA Activation of CRISPR-Cas12a for Sensitive and Selective Detection of Flunixin.
Article in ACS measurement science au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- An enhanced photoelectrochemical sensor based on CuBiMikrochimica acta · 2026Article
- A CRISPR-Cas12a amplified RNase activity sensor powered by gold nanoparticle-barcode DNA multipliers.Materials advances · 2026Article
- Nanopore Label-Free Monitoring of B-DNA and Z-DNA Conformational Transition in Real Time.ACS nano · 2026Article
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11 authors.
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Abstract
Flunixin, a nonsteroidal anti-inflammatory drug widely used in veterinary therapy, presents a risk of residues entering both the food supply and the environment. Therefore, developing sensitive methods for the treatment of flunixin is of great importance. Herein, we report a highly sensitive and selective CRISPR-Cas12a based fluorescent assay for flunixin measurement. By employing functionalized magnetic beads which carry double-stranded DNA (dsDNA) formed by a flunixin binding aptamer and its short partially complementary single-stranded DNA (ssDNA) hybridization probe and taking advantage of two split ssDNA strands to synergistically trigger the
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