Observational studyCanadian respiratory journal2025
Characteristics and Impact of Peripheral and Respiratory Muscle Weakness in Patients With Interstitial Lung Disease: A Cross-Sectional Observational Study.
Observational study in Canadian respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Diaphragm assessment by multimodal ultrasound imaging in patients with interstitial lung disease: a prospective observational study.Journal of thoracic disease · 2026Article
- Characteristics and Impact of Peripheral and Respiratory Muscle Weakness in Patients With Interstitial Lung Disease: A Cross-Sectional Observational Study.Canadian respiratory journal · 2025Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Background: Muscle weakness is a clinically significant complication of interstitial lung disease (ILD) that worsens dyspnea, fatigue, and quality of life, but its epidemiology and clinical impact remain understudied. Methods: In this cross-sectional study of 107 ILD patients, peripheral muscle weakness was defined as handgrip strength (HGS) < 28.0 kg (males) or < 18.0 kg (females), and respiratory muscle weakness as maximal inspiratory pressure (MIP) < 80% predicted. Assessments included pulmonary function, echocardiography, diaphragm ultrasound, 6-min walk distance (6MWD), short physical performance battery (SPPB), quality of life, and psychological status. Multivariate logistic regression identified the predictors of muscle weakness. Results: Peripheral muscle weakness (66.4%) was associated with older age, lower BMI, worse pulmonary function, reduced 6MWD, and higher right ventricular systolic pressure (RVSP) (all Conclusion: ILD patients with muscle weakness show impaired lung function, reduced physical capacity, and poorer quality of life. Calf circumference and 6MWD influence peripheral weakness, while biomass exposure and grip strength influence respiratory weakness.
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