Evidence map›Paper›PMID 41425123›Full record

ArticleClinical case reports2025

Manual Therapy in Conjunction With Other Multimodal Interventions in a Patient With Chronic Pain and Hypertension: A Case Report.

Craig P Hensley, Renzo Mendoza, Jennifer Ryan, Emmanuel Yung

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Craig P HensleyDepartment of Physical Therapy and Human Movement Sciences Northwestern University Chicago Illinois USA.ORCID https://orcid.org/0000-0003-4488-1332
Renzo MendozaDepartment of Therapy Services University of Illinois Health Systems Chicago Illinois USA.
Jennifer RyanDepartment of Physical Therapy and Human Movement Sciences Northwestern University Chicago Illinois USA.
Emmanuel YungDepartment of Physical Therapy, Crean College of Health and Behavioral Sciences Chapman University Orange California USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain and hypertension (HTN) are worldwide epidemics that are difficult to manage and frequently encountered as comorbid conditions in patient care. There is a paucity of information regarding the effect that manual therapy has on blood pressure (BP), particularly in those with chronic pain and HTN. This case report describes the management of a patient with chronic pain and HTN. The patient was a 41-year-old female with chronic multisite pain and multiple comorbidities, including HTN. Her BP at the initial evaluation was 147/78 with an oscillated device and 142/82 with a sphygmomanometer in the right arm and 144/80 in the left. The physical examination of the patient warranted a mid-thoracic thrust manipulation in supine. Manual therapy, education, meditation, and aerobic exercise were used throughout the episode of care (seven visits across 9 weeks). Upon reassessment after the thoracic thrust manipulation (5 min of quiet sitting), BP in the right arm was 105/65 with an oscillated device and 105/68 with a sphygmomanometer. Significant improvements in the Patient Specific Functional Scale, Lower Extremity Functional Scale, Numeric Pain Rating Scale, and BP were noted throughout the episode of care. She was able to return to her previous walking program. Improvements in pain, BP, and patient-reported outcomes were made in a patient with chronic multisite pain and HTN. Manual therapy, in conjunction with education, meditation, and aerobic exercise, may have aided in improving this patient's function and BP. Caution should be used when interpreting results from this case report. Future studies should examine the effects of physical therapy intervention, including manual therapy, in those with chronic pain and HTN. Manual therapy could be considered as an intervention to improve chronic pain and HTN.

Indexed as

cardiovascular disorderscomplementary and alternative medicinephysical therapy

Identifiers

PMID41425123
PMCPMC12717022

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.