Evidence map›Paper›PMID 41425084›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

Uncovering barriers to early diagnosis of Alzheimer's disease: a European perspective.

David A Pérez-Martínez, Anne-Charlotte Jarry, Gabriel Martino, Giancarlo Pesce, Izabela Pieniazek, Jenny Presto, Patryk Miernik, Roman Casciano, Kristian Steen Frederiksen

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David A Pérez-MartínezHead of Neurology Department Hospital Universitario 12 de Octubre Madrid Spain.
Anne-Charlotte JarryNovo Nordisk Copenhagen Denmark.ORCID https://orcid.org/0009-0004-1770-6226
Gabriel MartinoNovo Nordisk Copenhagen Denmark.
Giancarlo PesceEvidence and Access Certara Milan Italy.
Izabela PieniazekEvidence and Access Certara Krakow Poland.
Jenny PrestoNovo Nordisk Malmö Sweden.
Patryk MiernikEvidence and Access Certara Krakow Poland.
Roman CascianoEvidence and Access Certara Radnor Pennsylvania USA.
Kristian Steen FrederiksenDanish Dementia Research Centre Department of Neurology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTimely and accurate diagnosis of early Alzheimer's disease (AD) is critical to maximizing the potential benefits of disease-modifying therapies; however, it remains a challenge in clinical practice.

methodsA double-blind survey was conducted among general practitioners (GPs;

resultsGPs are usually the first point of contact for patients with mild cognitive impairment (MCI)/AD. Only 30% of patients received a formal diagnosis of AD during the MCI stage, and it took patients 15.2 months from symptom onset to their first primary care visit. The most common challenges identified by HCPs were referral times, lack of effective treatment, and resource and time constraints. DISCUSSION: Systemic reforms are required to remove barriers in early AD diagnosis, including tailored training and coordinated care between GPs and AD specialists. Highlights: Timely diagnosis of eAD remains a major challenge in clinical practice.Only one-third of patients received a formal diagnosis of AD during the MCI stage.It took patients 15.2 months from symptom onset to first primary care visit.Key diagnostic barriers include referral delays and lack of effective treatments.Addressing these issues may improve eAD diagnosis and timely intervention.

Indexed as

AD diagnosisAlzheimer's diseasebarriers to diagnosisdementiaearly diagnosisgeneral practitionersMCIspecialist physicians

Identifiers

PMID41425084
PMCPMC12715703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.