ArticleIndian journal of sexually transmitted diseases and AIDS
A retrospective analysis of the epidemiological factors, high-risk groups, and treatment response in patients of anogenital warts attending a tertiary care hospital in Northern India.
Article in Indian journal of sexually transmitted diseases and AIDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Objectives: There is a paucity of studies analyzing risk factors and outcomes of treatment of genital warts. Our study evaluated the prevalence of various epidemiological factors in high-risk populations of men versus women, among persons living with HIV (PLHIV) patients and men who have sex with men (MSM) patients, and the comparative efficacy of trichloroacetic acid (TCA) versus podophyllum toxin, among other modalities, in the treatment of anogenital warts. Materials and Methods: It was a retrospective observational study done over 2.5 years including 294 subjects. Demographic, clinical, and epidemiological data were extracted from registration records and analyzed. Results: Extra/premarital contact, presence of multiple sexual partners, and addiction were significantly higher in men, and illiteracy/unemployment and unprotected intercourse were significantly higher risk factors in females. Multiple sexual partners and addiction as well as compliance to treatment were found to be significantly more prevalent in PLHIV patients versus non-PLHIV. Extra or premarital contact, multiple sexual partners, and average number of sexual partners were significantly higher in MSM with men patients versus heterosexual patients. Among the 294 patients, 137 (46.5%) patients were compliant with the treatment, out of which 122 (89.1%) showed complete resolution, and 10.9% of patients had partial resolution. A total of 110 (37.4%) patients were treated with TCA (70%-90%), and 37.4% achieved complete resolution in 4.6 months on average. Podophyllum resin 20% was used to treat 184 (62.5%) patients, with 62.5% resolving in an average of 4.5 months. Conclusion: The study highlights the need for targeted screening for epidemiological factors in often-overlooked high-risk population and emphasizes the importance of future research to optimize treatment strategies.
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