Evidence map›Paper›PMID 41424862›Full record

ArticleTheranostics2026

Macrophage Nrf1/NFE2L1-Foxo1 axis controls liver fibrosis by modulation of mitochondrial reprogramming.

Yuanbang Lin, Xiyun Bian, Yao Yao, Jingman Xu, Yingli Cao, Qiong Wu, Wen Ning, Lian Li, Mingwei Sheng, Fengmei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuanbang LinDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Xiyun BianCentral Laboratory, Tianjin Fifth Central Hospital, Tianjin 300450, China.
Yao YaoDepartment of Hepatology and Gastroenterology, Tianjin First Central Hospital, Tianjin 300192, China.
Jingman XuSchool of Public Health, North China University of Science and Technology, Tangshan 063000, China.
Yingli CaoDepartment of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China.
Qiong WuDepartment of Hepatology and Gastroenterology, Tianjin First Central Hospital, Tianjin 300192, China.
Wen NingCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Lian LiCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Mingwei ShengDepartment of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China.
Fengmei WangDepartment of Hepatology and Gastroenterology, Tianjin First Central Hospital, Tianjin 300192, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Forkhead Box Protein O1Liver CirrhosisMacrophagesMitochondriaNuclear Respiratory Factor 1AnimalsCellular ReprogrammingDisease Models, AnimalHumansKruppel-Like Transcription FactorsLiverMaleMiceMice, Inbred C57BLMice, KnockoutNF-E2-Related Factor 1Forkhead Box Protein O1FOXO1 protein, humanFoxo1 protein, mouseKruppel-Like Transcription FactorsNfe2L1 protein, mouseNF-E2-Related Factor 1NRF1 protein, humanNuclear Respiratory Factor 1inflammationinnate immunityliver fibrosismitochondria

Identifiers

PMID41424862
PMCPMC12712952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.