Evidence map›Paper›PMID 41424860›Full record

ArticleTheranostics2026

Neuronal mitochondrial disaggregase CLPB ameliorates Huntington's disease pathology in mice.

Hyeonho Kim, Gaeun Hyun, Seunghye Kim, Changmo Yu, Young-Gi Hong, Jihyeon Yu, Sangsu Bae, Hyun-Woo Rhee, Jaewon Ko, Ji Won Um

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hyeonho KimDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea.
Gaeun HyunDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea.
Seunghye KimDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea.
Changmo YuDepartment of Chemistry, Seoul National University, Seoul 08826, Korea.
Young-Gi HongDepartment of Chemistry, Seoul National University, Seoul 08826, Korea.
Jihyeon YuGenomic Medicine Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Sangsu BaeGenomic Medicine Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Hyun-Woo RheeDepartment of Chemistry, Seoul National University, Seoul 08826, Korea.
Jaewon KoDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea.
Ji Won UmDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endopeptidase ClpHuntington DiseaseMitochondriaNeuronsAnimalsCorpus StriatumDisease Models, AnimalHEK293 CellsHumansHuntingtin ProteinMaleMiceProtein AggregatesSynapsesEndopeptidase ClpHTT protein, humanHuntingtin ProteinProtein AggregatesClpBdisaggregaseHuntington's diseaseinhibitory synapsemitochondriastriatum

Identifiers

PMID41424860
PMCPMC12712926

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.