Evidence map›Paper›PMID 41424856›Full record

ArticleTheranostics2026

Microglial TIA1-mediated stress granules promote neuroinflammation and aggravate neuron loss in mice after ischemic stroke by inhibiting IGF2 signaling.

Yiming Qian, Hong Yu, Jianhong Dong, Jinyuan Liu, Jiaqi Han, Tianwen Zheng, Wei Zhang, Lipei Wang, Zhihui Huang, Ying Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yiming QianDepartment of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine, Hangzhou 310006, Zhejiang, China.
Hong YuSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Jianhong DongSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Jinyuan LiuSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Jiaqi HanSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Tianwen ZhengSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Wei ZhangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Lipei WangSchool of Basic Medical Sciences, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Zhihui HuangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Ying WangDepartment of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine, Hangzhou 310006, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Insulin-Like Growth Factor IIIschemic StrokeMicrogliaNeuroinflammatory DiseasesNeuronsStress GranulesT-Cell Intracellular Antigen-1AnimalsCell LineDisease Models, AnimalMaleMiceMice, Inbred C57BLMice, KnockoutSignal TransductionInsulin-Like Growth Factor IIT-Cell Intracellular Antigen-1Tia1 protein, mouseIGF2ischemic strokeneuroinflammationstress granulesTIA1

Identifiers

PMID41424856
PMCPMC12713190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.