Evidence map›Paper›PMID 41424752›Full record

ArticleCase reports in infectious diseases2025

Warfarin-Linezolid Interaction: A Case of Severe Coagulopathy.

Aniqa Batool, Waqar Khan, Muhammad Mohsin

Abstract read
In one paragraph

Article in Case reports in infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Warfarin-Linezolid Interaction: A Case of Severe Coagulopathy.Case reports in infectious diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aniqa BatoolNational Institute of Cardiovascular Diseases, Karachi, Pakistan, nicvd.gov.bd.ORCID https://orcid.org/0000-0002-2730-4974
Waqar KhanNational Institute of Cardiovascular Diseases, Karachi, Pakistan, nicvd.gov.bd.
Muhammad MohsinNational Institute of Cardiovascular Diseases, Karachi, Pakistan, nicvd.gov.bd.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Warfarin, a vitamin K antagonist, is commonly used for atrial fibrillation (AF), venous thromboembolism (VTE), and mechanical heart valves. Linezolid, an oxazolidinone antibiotic, is used to treat severe infections caused by Gram-positive bacteria. A fatal drug interaction of linezolid and warfarin was reported in this case, highlighting the close monitoring of international normalized ratio (INR) when co-administering these drugs. Case Presentation: A 62-year-old female with severe mitral stenosis (MS) and moderate mitral regurgitation (MR) was diagnosed with mitral valve vancomycin-resistant Conclusion: This case highlights the potential for severe coagulopathy when warfarin and linezolid are co-administered and underscores the importance of close and frequent INR monitoring.

Indexed as

atrial fibrillationdrug–drug interactioninfective endocarditislinezolidwarfarin

Identifiers

PMID41424752
PMCPMC12714091

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.