Evidence map›Paper›PMID 41424677›Full record

ArticleHealth science reports2025

Evaluation of Inhaled Colistin/Fosfomycin as an Adjunctive Treatment for Ventilator-Associated Pneumonia: A Preliminary Study.

Atousa Hakamifard, Mohammad Reza Mohammadi, Alireza Homayouni, Farzin Khorvash, Saeed Abbasi, Behrooz Ataei, Mahnaz Momenzadeh

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Atousa HakamifardInfectious Diseases and Tropical Medicine Research Center Isfahan University of Medical Sciences Isfahan Iran.
Mohammad Reza MohammadiInfectious Diseases and Tropical Medicine Research Center Isfahan University of Medical Sciences Isfahan Iran.
Alireza HomayouniResearch and Development Department Goldaru Pharmaceutical Company Isfahan Iran.
Farzin KhorvashInfectious Diseases and Tropical Medicine Research Center Isfahan University of Medical Sciences Isfahan Iran.
Saeed AbbasiAnesthesiology and Critical Care Research Center Isfahan University of Medical Sciences Isfahan Iran.
Behrooz AtaeiInfectious Diseases and Tropical Medicine Research Center Isfahan University of Medical Sciences Isfahan Iran.
Mahnaz MomenzadehDepartment of Clinical Pharmacy and Pharmacy Practice Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0001-7136-3069

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Ventilator-associated pneumonia (VAP) caused by gram-negative bacteria is associated with significant complications, mortality, and resource utilization. Over the past decade, there has been growing interest in using fosfomycin to treat multidrug-resistant gram-negative infections, particularly when limited viable options remain. This study aimed to investigate the efficacy of inhaled colistin/fosfomycin as an adjunctive treatment for VAP. Methods: In this triple-blind clinical trial, participants with VAP caused by extensively drug-resistant (XDR) Results: While the differences were not statistically significant ( Conclusion: The study demonstrated that the addition of inhaled colistin/fosfomycin to the treatment regimen may result in faster recovery and shorter treatment duration for patients with VAP caused by XDR

Indexed as

Acinetobacter baumanniicolistinfosfomycinventilator‐associated pneumonia

Identifiers

PMID41424677
PMCPMC12715318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.